Chemogenomics Knowledgebased Polypharmacology Analyses of Drug Abuse Related G-Protein Coupled Receptors and Their Ligands

• Main Authors: Xiang-Qun eXie (Author), Lirong eWang (Author), haibin eLiu (Author), Qin eOuyang (Author), Cheng eFang (Author), Weiwei eSu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug abuse (DA) and addiction is a complex illness, broadly viewed as a neurobiological impairment with genetic and environmental factors that influence its development and manifestation. Abused substances can disrupt the activity of neurons by interacting with many proteins, particularly G-protein...