Syntheses of Radioiodinated Pyrimidine-2,4,6-Triones as Potential Agents for Non-Invasive Imaging of Matrix Metalloproteinases

Dysregulated expression or activation of matrix metalloproteinases (MMPs) is observed in many kinds of live-threatening diseases. Therefore, MMP imaging for example with radiolabelled MMP inhibitors (MMPIs) potentially represents a valuable tool for clinical diagnostics using non-invasive single pho...

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Bibliographic Details
Main Authors: Hans-Jörg Breyholz (Author), Klaus Kopka (Author), Michael Schäfers (Author), Stefan Wagner (Author)
Format: Book
Published: MDPI AG, 2017-05-01T00:00:00Z.
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