PEAR1 is not a major susceptibility gene for cardiovascular disease in a Flemish population

• Main Authors: Wen-Yi Yang (Author), Thibault Petit (Author), Nicholas Cauwenberghs (Author), Zhen-Yu Zhang (Author), Chang-Sheng Sheng (Author), Lutgarde Thijs (Author), Erika Salvi (Author), Benedetta Izzi (Author), Christophe Vandenbriele (Author), Fang-Fei Wei (Author), Yu-Mei Gu (Author), Lotte Jacobs (Author), Lorena Citterio (Author), Simona Delli Carpini (Author), Cristina Barlassina (Author), Daniele Cusi (Author), Marc F. Hoylaerts (Author), Peter Verhamme (Author), Tatiana Kuznetsova (Author), Jan A. Staessen (Author)
• Format: Book
• Published: BMC, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Platelet Endothelial Aggregation Receptor 1 (PEAR1), a membrane protein highly expressed in platelets and endothelial cells, plays a role in platelet contact-induced activation, sustained platelet aggregation and endothelial function. Previous reports implicate PEAR1 rs12041331 a...