A qualitative investigation of RANKL, RANK and OPG in a rat model of transient ankylosis

Introduction: Previous studies have found ankylosis occurs as a part of the inflammatory process of aseptic root resorption initiated in a rat model.1 The physiologic mechanisms behind the development of dentoalveolar ankylosis and healing response are still unclear. While receptor activator of nucl...

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Main Authors: Curl Linda (Author), Tan Chien Wei (Author), Dreyer Craig W. (Author), Sampson Wayne (Author)
Format: Book
Published: Sciendo, 2014-11-01T00:00:00Z.
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Summary:Introduction: Previous studies have found ankylosis occurs as a part of the inflammatory process of aseptic root resorption initiated in a rat model.1 The physiologic mechanisms behind the development of dentoalveolar ankylosis and healing response are still unclear. While receptor activator of nuclear factor-κβ ligand (RANKL), receptor activator of nuclear factor-κβ (RANK) and osteoprotegerin (OPG) have gained momentum in the understanding of resorption, no study to date has investigated their role in dentoalveolar ankylosis.
Item Description:2207-7480
10.2478/aoj-2014-0011