Dexmedetomidine inhibits the NF-κB pathway and NLRP3 inflammasome to attenuate papain-induced osteoarthritis in rats

• Main Authors: Fang Cheng (Author), Feng-Feng Yan (Author), Yue-Peng Liu (Author), Yan Cong (Author), Ke-Fu Sun (Author), Xue-Ming He (Author)
• 格式: 图书
• 出版: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Context: Dexmedetomidine (Dex) has been reported to have an anti-inflammatory effect. However, its role on osteoarthritis (OA) has not been explored. Objective: This study investigates the effect of Dex on OA rat model induced by papain. Materials and methods: The OA Wistar rat model was induced by...