CFTR Modulator Therapy for Rare CFTR Mutants

• Hauptverfasser: Marco Mergiotti (VerfasserIn), Alessandra Murabito (VerfasserIn), Giulia Prono (VerfasserIn), Alessandra Ghigo (VerfasserIn)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Cystic fibrosis (CF), the most common genetic disease among the Caucasian population, is caused by mutations in the gene encoding for the CF transmembrane conductance regulator (CFTR), a chloride epithelial channel whose dysfunction results in severe airway obstruction and inflammation, eventually l...