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Rare histologic transformation of a CTNNB1 (β-catenin) mutated prostate cancer with aggressive clinical course

Abstract Background Catenin (Cadherin-Associated Protein), Beta 1 (CTNNB1) genomic alterations are rare in prostate cancer (PCa). Gain-of-function mutations lead to overexpression of β-catenin, with consequent hyperactivation of the Wnt/β-catenin signaling pathway, implicated in PCa progression and...

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Main Authors:	Dilara Akhoundova (Author), Stefanie Fischer (Author), Joanna Triscott (Author), Marika Lehner (Author), Phillip Thienger (Author), Sina Maletti (Author), Muriel Jacquet (Author), Dinda S.H. Lubis (Author), Lukas Bubendorf (Author), Wolfram Jochum (Author), Mark A. Rubin (Author)
Format:	Book
Published:	BMC, 2024-06-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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