Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae

Treatment options for extended-spectrum β-lactamase-producing Enterobacteriaceae are limited. Piperacillin-tazobactam and cefepime represent potential alternative treatment options; however, large prospective studies are lacking. This review evaluates the current literature regarding use of piperaci...

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Main Authors: Allison M. Gibble (Author), Alan E. Gross (Author), Angela M. Huang (Author)
Format: Book
Published: MDPI AG, 2015-12-01T00:00:00Z.
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700 1 0 |a Angela M. Huang  |e author 
245 0 0 |a Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae 
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520 |a Treatment options for extended-spectrum β-lactamase-producing Enterobacteriaceae are limited. Piperacillin-tazobactam and cefepime represent potential alternative treatment options; however, large prospective studies are lacking. This review evaluates the current literature regarding use of piperacillin-tazobactam and cefepime for the treatment of extended-spectrum β-lactamase-producing Enterobacteriaceae. Antimicrobial stewardship programs can play a key role in guiding the best practices for the management of these challenging infections. 
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690 |a extended-spectrum beta-lactamases 
690 |a piperacillin-tazobactam 
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690 |a carbapenems 
690 |a Therapeutics. Pharmacology 
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786 0 |n Antibiotics, Vol 4, Iss 4, Pp 653-666 (2015) 
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