Gastrin Attenuates Renal Ischemia/Reperfusion Injury by a PI3K/Akt/Bad-Mediated Anti-apoptosis Signaling

• Main Authors: Chao Liu (Author), Ken Chen (Author), Huaixiang Wang (Author), Ye Zhang (Author), Xudong Duan (Author), Yuanzheng Xue (Author), Hongye He (Author), Yu Huang (Author), Zhi Chen (Author), Hongmei Ren (Author), Hongyong Wang (Author), Chunyu Zeng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ischemic/reperfusion (I/R) injury is the primary cause of acute kidney injury (AKI). Gastrin, a gastrointestinal hormone, is involved in the regulation of kidney function of sodium excretion. However, whether gastrin has an effect on kidney I/R injury is unknown. Here we show that cholecystokinin B...