Total and Unbound Pharmacokinetics of Cefiderocol in Critically Ill Patients

• Автори: Noël Zahr (Автор), Saik Urien (Автор), Benoit Llopis (Автор), Gaëlle Noé (Автор), Nadine Tissot (Автор), Kevin Bihan (Автор), Helga Junot (Автор), Clémence Marin (Автор), Bochra Mansour (Автор), Charles-Edouard Luyt (Автор), Alexandre Bleibtreu (Автор), Christian Funck-Brentano (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: Cefiderocol is a siderophore cephalosporin antibiotic active against Gram-negative bacteria, including extended-spectrum beta-lactamase and carbapenemase-producing strains. The pharmacokinetics of cefiderocol has been studied in healthy subjects and particularly in phase II and III studi...