Early Interleukin-22 and Neutrophil Proteins Are Correlated to Future Lung Damage in Children With Cystic Fibrosis

• Main Authors: Julie Renwick (Author), Emma Reece (Author), Jamie Walsh (Author), Ross Walsh (Author), Thara Persaud (Author), Cathal O'Leary (Author), Seamas C. Donnelly (Author), Peter Greally (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic Fibrosis (CF) lung damage begins early in life. Lung function decline is associated with pulmonary infections, neutrophil infiltration and inflammation. In CF, neutrophils have an altered phenotype. In this pilot study, we aimed to determine if signals of dysfunctional neutrophil responses we...