Corneal Permeability and Uptake of Twenty-Five Drugs: Species Comparison and Quantitative Structure-Permeability Relationships
The purpose of this study was to determine corneal permeability and uptake in rabbit, porcine, and bovine corneas for twenty-five drugs using an N-in-1 (cassette) approach and relate these parameters to drug physicochemical properties and tissue thickness through quantitative structure permeability...
Saved in:
Main Authors: | Cleildo P. Santana (Author), Brock A. Matter (Author), Madhoosudan A. Patil (Author), Armando Silva-Cunha (Author), Uday B. Kompella (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2023-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Brain Distribution and Metabolism of Flupirtine, a Nonopioid Analgesic Drug with Antiseizure Effects, in Neonatal Rats
by: Madhoosudan A. Patil, et al.
Published: (2018) -
Enhanced Corneal Penetration of a Poorly Permeable Drug Using Bioadhesive Multiple Microemulsion Technology
by: Mohamed Moustafa Ibrahim, et al.
Published: (2020) -
Permeability of Buccal Mucosa
by: Apipa Wanasathop, et al.
Published: (2021) -
Polyols Permeability on Caco-2 Cells and Their Effects on Transport of Low-Permeability Drugs
by: Damien Truffin, et al.
Published: (2023) -
Redox Regulation of Microvascular Permeability: IL-1β Potentiation of Bradykinin-Induced Permeability Is Prevented by Simvastatin
by: Felipe Freitas, et al.
Published: (2020)