Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight
Objective: Intestinal metabolism might play a greater role in regulating whole body metabolism than previously believed. We aimed to enhance enterocyte metabolism in mice and investigate if it plays a role in diet-induced obesity (DIO) and its comorbidities. Methods: Using the cre-loxP system, we ov...
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Main Authors: | Deepti Ramachandran (Author), Rosmarie Clara (Author), Shahana Fedele (Author), Junmin Hu (Author), Endre Lackzo (Author), Jing-Yi Huang (Author), Eric Verdin (Author), Wolfgang Langhans (Author), Abdelhak Mansouri (Author) |
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Format: | Book |
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Elsevier,
2017-10-01T00:00:00Z.
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