Hepatic protective effect of grape seed proanthocyanidin extract against Gleevec-induced apoptosis, liver Injury and Ki67 alterations in rats

• Main Authors: Nawal Mohammed Al-Rasheed (Author), Thanaa Ahmed El-Masry (Author), Ehab Tousson (Author), Hanan Mohammad Hassan (Author), Areej Al-Ghadeer (Author)
• Format: Book
• Published: Universidade de São Paulo, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Gleevec (imatinib) is an antineoplastic chemotherapeutic agent used in the treatment of many types of cancer. The current study was conducted to examine the possible modifying effects of grape seeds proanthocyandins extract (GSPE) against apoptosis, liver injury and Ki67 alterations induced...