A Rhein-Based Derivative Targets <i>Staphylococcus aureus</i>

• Main Authors: Xiaojia Liu (Author), Yuan Liu (Author), Meirong Song (Author), Kui Zhu (Author), Jianzhong Shen (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The rise in antibiotic-resistant bacteria highlights the need for novel antimicrobial agents. This study presents the design and synthesis of a series of rhein (RH)-derived compounds with improved antimicrobial properties. The lead compound, RH<b>17</b>, exhibited a potent antibacterial...