Beta cell protective effect of Curcuma longa and Piper nigrum in cytokine cocktail induced apoptosis in Min6 pancreatic beta cells

• Main Authors: Hemangee Damame (Author), Sheetalnath Rooge (Author), Rahul Patil (Author), Chandramukhi Garad (Author), Akalpita Arvindekar (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: : Type 1 diabetes mellitus is characterized by loss of beta cell mass and insulin insufficiency. Beta cell apoptosis and destruction by cytotoxic T lymphocytes and pro-inflammatory cytokines like IL-1β, TNF-α and IFN-γ appears to represent a key event in pathogenesis of type 1 diabetes m...