Small heat shock proteins mediate cell-autonomous and -nonautonomous protection in a Drosophila model for environmental-stress-induced degeneration

• Main Authors: Fumiko Kawasaki (Author), Noelle L. Koonce (Author), Linda Guo (Author), Shahroz Fatima (Author), Catherine Qiu (Author), Mackenzie T. Moon (Author), Yunzhen Zheng (Author), Richard W. Ordway (Author)
• Format: Book
• Published: The Company of Biologists, 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cell and tissue degeneration, and the development of degenerative diseases, are influenced by genetic and environmental factors that affect protein misfolding and proteotoxicity. To better understand the role of the environment in degeneration, we developed a genetic model for heat shock (HS)-stress...