Distinct Functions of Neutrophil in Cancer and Its Regulation

Neutrophils are the most abundant of all white blood cells in the human circulation and are usually associated with inflammation and with fighting infections. In recent years the role immune cells play in cancer has been a matter of increasing interest. In this context the function of neutrophils is...

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Bibliographic Details
Main Authors: Zvi Granot (Author), Jadwiga Jablonska (Author)
Format: Book
Published: Hindawi Limited, 2015-01-01T00:00:00Z.
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Summary:Neutrophils are the most abundant of all white blood cells in the human circulation and are usually associated with inflammation and with fighting infections. In recent years the role immune cells play in cancer has been a matter of increasing interest. In this context the function of neutrophils is controversial as neutrophils were shown to possess both tumor promoting and tumor limiting properties. Here we provide an up-to-date review of the pro- and antitumor properties neutrophils possess as well as the environmental cues that regulate these distinct functions.
Item Description:0962-9351
1466-1861
10.1155/2015/701067