Transporter-centric view of urate metabolism: From genome-wide association study to pathophysiology

• Autor principal: Hiroyuki Sakurai (Autor)
• Formato: Livro
• Publicado em: Japanese Society of Physical Fitness and Sports Medicine, 2012-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

While urate is an important anti-oxidant molecule in the body, high plasma levels of urate cause morbidity including urate crystal deposition in joints (gout) and stone formation in the urinary tract. Because urate is an end product of purine metabolism, it must be excreted from the body via the kid...