Detection of chlamydial antibodies in women with pelvic inflammatory disease and infertility

Objective: To detect the chlamydial antibodies in women with pelvic inflammatory disease (PID) and infertility. Method: This study was carried out on 72 patients suffering from pelvic inflammatory disease and/ or infertility who were admitted in the indoor wards and those attending the out patient d...

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Main Authors: Ramona Perhar (Author), Shilpi Rawat (Author), Ruchi Pandey (Author)
Format: Book
Published: Barpeta Obstetrics and Gynaecological Society, 2020-01-01T00:00:00Z.
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001 doaj_ad77fc29e86b4fe3bd73840056e8a990
042 |a dc 
100 1 0 |a Ramona Perhar  |e author 
700 1 0 |a Shilpi Rawat  |e author 
700 1 0 |a Ruchi Pandey  |e author 
245 0 0 |a Detection of chlamydial antibodies in women with pelvic inflammatory disease and infertility 
260 |b Barpeta Obstetrics and Gynaecological Society,   |c 2020-01-01T00:00:00Z. 
500 |a 10.21276/obgyn.2020.6.2.8 
500 |a 2454-2334 
500 |a 2454-2342 
520 |a Objective: To detect the chlamydial antibodies in women with pelvic inflammatory disease (PID) and infertility. Method: This study was carried out on 72 patients suffering from pelvic inflammatory disease and/ or infertility who were admitted in the indoor wards and those attending the out patient department. Control group comprised of relatives of patients, nursing staff and other staff of the hospital who did not have any present or past history of PID or infertility. Result: IgG and IgA antibodies were detectable in 50% cases of PID while IgG alone were detectable in 75 % cases of PID. Compared with the control group, the differences was statistically significant (p value < 0.001). Statistically significant (p<0.001) chlamydial IgG antibodies among the infertile subjects with fallopian tube disorders was found compared to the infertile subjects with normal tubes. IgG antibodies Chlamydia were positive in 1:64 dilution in 75% cases of PID and IgA antibodies Chlamydia were positive in 1:16 dilution in 50% cases of PID. Assay for IgG in infertile women, 10 % cases were positive at 1:128 dilution. Ten (33.33%) cases of infertility were positive for IgA antibodies (1:16dilution). Results are statistically significant as compared to control group (p value <0.001). Conclusion: It appears that testing for IgG antibodies at a serum dilution of 1:64 and for IgA antibodies at a dilution of 1:16 by the IPA test comprises the best combination for the differentiation between the PID patients and apparently healthy controls, and it is suggested that this be used as a marker of active C. trachomatis infection. 
546 |a EN 
690 |a chlamydia antibody 
690 |a infertility 
690 |a pid 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n New Indian Journal of OBGYN, Vol 6, Iss 2, Pp 101-105 (2020) 
787 0 |n https://journal.barpetaogs.co.in/pdf/06101.pdf 
787 0 |n https://doaj.org/toc/2454-2334 
787 0 |n https://doaj.org/toc/2454-2342 
856 4 1 |u https://doaj.org/article/ad77fc29e86b4fe3bd73840056e8a990  |z Connect to this object online.