Cover Image

Pharmacokinetics comparison of two pegylated interferon alfa formulations in healthy volunteers

Abstract Background Several countries have used pegylation technology to improve the pharmacokinetic properties of essential drugs. Recently, a novel interferon alfa-2b protein conjugated to four-branched 12 kDa polyethylene glycol molecules was developed jointly between Cuba and Brazil. The aim of...

Full description

Saved in:

Bibliographic Details
Main Authors:	Marisa Boff Costa (Author), Paulo Dornelles Picon (Author), Guilherme Becker Sander (Author), Hugo Nodarse Cuni (Author), Carmen Valenzuela Silva (Author), Rolando Páez Meireles (Author), Ana Carolina Magalhães Andrade Góes (Author), Nadia Maria Batoreu (Author), Maria de Lourdes de Sousa Maia (Author), Elizabeth Maciel Albuquerque (Author), Denise Cristina de Souza Matos (Author), Pedro Lopez Saura (Author)
Format:	Book
Published:	BMC, 2018-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Subcutaneous Sarcoidosis during Pegylated Interferon Alfa and Ribavirin Treatment for Chronic Hepatitis C
by: R. Rodríguez-Lojo, et al.
Published: (2010)

Evaluación de la Inmunogenicidad del Interferón Alfa 2B Humano Recombinante en pacientes con Hepatitis crónica y Hemangiomas de la infancia. Resumen
by: Barbara Torres Rives, et al.
Published: (2005)

Frequency Of Depressive And Anxiety Symptoms Among Patients On Interferon And Pegylated Interferon
by: Muhammad Waseem Shaikh, et al.
Published: (2024)

Revisão sistemática da eficácia do interferon alfa (convencional, peguilado) e lamivudina para o tratamento da hepatite crônica B Efficacy of interferon (conventional, pegylated) and lamivudine for treatment of chronic hepatitis B: a systematic review
by: Alessandra Maciel Almeida, et al.
Published: (2009)

INTERSTICIAL PNEUMONITIS, CAUSED BY PEGYLATED INTERFERON ALFA-2A IN A 4 MONTHS CHILD WITH GIGANTIC KAPOSI'S HAEMANGIOEPITHELIOM AND KASABACH - MERRIT PHENOMENON: A CASE REPORT
by: S. S. Postnikov, et al.
Published: (2022)

Individualized treatment of chronic hepatitis C with pegylated interferon and ribavirin
by: Roberto J Carvalho-Filho, et al.
Published: (2010)

Tratamento clínico do linfangioma com alfa-2a-interferon Treatment of lymphangioma with interferon-alpha-2a
by: Reynaldo J.S.P. de Souza, et al.
Published: (2001)

Non-pegylated and Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma and the Risk of Severe Ocular Side-effects
by: Jana D. Albrecht, et al.
Published: (2022)

Pegylated Interferon (Alone or With Ribavirin) for Chronic Hepatitis C in Haemodialysis Population
by: Mario Espinosa, et al.
Published: (2015)

Pegylated Interferon Associated Thyroidal Dysfunction Among Hepatitis C Patients
by: Nida Sajid, et al.
Published: (2024)

Profile of PEGylated interferon beta in the treatment of relapsing-remitting multiple sclerosis
by: Cocco E, et al.
Published: (2015)

Systematic review and meta-analysis: de novo combination of nucleos(t)ide analogs and pegylated interferon alpha versus pegylated interferon alpha monotherapy for the functional cure of chronic hepatitis B
by: Na Wei, et al.
Published: (2024)

Interferon-alfa in the management of cystic craniopharyngioma in children under 5 years of age
by: Jose Roberto Tude Melo, et al.
Published: (2021)

Erythema annulare centrifugum-like eruption associated with pegylated interferon treatment for hepatitis C
by: Mark Naccarato, et al.
Published: (2013)

Erosive oral lichen planus after pegylated-interferon therapy for chronic hepatitis B
by: Ellie Choi, MMed, MRCP, et al.
Published: (2018)

Pegylated-interferon-alpha treatment modulating the immune response of cytotoxic lymphocytes in cervical intraepithelial neoplasia
by: Letícia Montes Stark, et al.
Published: (2021)

Thyroid disturbances in children treated with combined pegylated interferon-alpha and ribavirin for chronic hepatitis C
by: Yasser K. Rashed, et al.
Published: (2020)

Activins and Follistatin in Chronic Hepatitis C and Its Treatment with Pegylated-Interferon-α Based Therapy
by: Bassem Refaat, et al.
Published: (2015)

Epidermodisplasia verruciforme: tratamento combinado com acitretina e interferon alfa-2a Epidermodysplasia verruciformis: combined treatment with acitretin and interferon alpha-2a
by: Cristiana Silveira Silva, et al.
Published: (2006)

Use of Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma: A Retrospective Case Collection
by: Janika Gosmann, et al.
Published: (2023)

Psoriasis induced by Interferon alfa-2a and ribavirin in a patient followed for hepatitis C
by: N. Amraoui, et al.
Published: (2015)

Comparison of peginterferon alfa-2a and alfa-2b for treatment of patients with chronic hepatitis C:a retrospective study using the Japanese Interferon Database
by: Sato I, et al.
Published: (2014)

Adverse Skin Reactions due to Ribavirin in Hepatitis C Combination Therapy with Pegylated Interferon-α2a
by: Masahisa Shindo, et al.
Published: (2013)

Pegylated Interferon-α Modulates Liver Concentrations of Activin-A and Its Related Proteins in Normal Wistar Rat
by: Bassem Refaat, et al.
Published: (2015)

A Severe Case of Lymphomatoid Papulosis Type E Successfully Treated with Interferon-Alfa 2a
by: Aslı Bilgiç Temel, et al.
Published: (2017)

Polyethylene Glycol Exposure with Antihemophilic Factor (Recombinant), PEGylated (rurioctocog alfa pegol) and Other Therapies Indicated for the Pediatric Population: History and Safety
by: Reinhard Stidl, et al.
Published: (2018)

Prediction of sustained virologic responses to combination therapy of pegylated interferon-α and ribavirin in patients with chronic hepatitis C infection
by: Mona H Ismail
Published: (2013)

Impact of "Sambhav" Program (Financial Assistance and Counselor Services) on Hepatitis C Pegylated Interferon Alpha Treatment Initiation in India
by: Ajit Sood, et al.
Published: (2018)

Pegylated interferon 2a and 2b in combination with ribavirin for the treatment of chronic hepatitis C in HIV infected patients
by: Ravinder Dhillon, et al.
Published: (2008)

Investigation of Cytotoxic Effects of Recombinant Human Interferon Lambda-1 and Its Pegylated Form on Human Conjunctival Epithelial Cells
by: N. A. Kikhtenko, et al.
Published: (2021)

The efficacy of pegylated interferon alpha-2a and entecavir in HBeAg-positive children and adolescents with chronic hepatitis B
by: Yi He, et al.
Published: (2022)

Polymorphism of IL-28B Gene (rs12979860) in HCV Genotype 1 Patients Treated by Pegylated Interferon and Ribavirin
by: Fahimeh Safarnezhad Tameshkel, et al.
Published: (2016)

Stabilitas Ekspresi Kerangka Baca Terbuka Penyandi Interferon Alfa-2a pada Yeast Pichia pastoris
by: Try Kurniawan Mutaqien, -
Published: (2017)

The effectiveness of the use of the drug recombinant interferon alfa-2b for the prevention of acute respiratory infections in preschool children
by: S. A. Drakina, et al.
Published: (2019)

Тhe prophylactic efficacy of a recombinant interferon alfa-2b drug in children with bronchial asthma
by: Y. I. Zhakov, et al.
Published: (2019)

CLINICAL AND IMMUNOLOGICAL EFFICACY OF THE RECOMBINANT INTERFERON alfa-2b OF ACUTE EPSTEIN-BARR VIRAL MONONUCLEOSIS IN PRESCHOOL CHILDREN
by: V. N. Timchenko, et al.
Published: (2016)

Interferon alfa-2b in complex therapy of intrauterine infection in newborns from mothers with bacterial-viral mixt-infections
by: O.O. Loshak, et al.
Published: (2019)

Simple score to predict risk of hepatocellular carcinoma in chronic hepatitis C patients with advanced fibrosis after pegylated interferon and ribavirin therapy
by: Hu CC, et al.
Published: (2018)

The use in pediatrics of recombinant interferon alfa-2b preparations in the dosage form rectal suppositories: whom? when? which ones?
by: M. S. Savenkova, et al.
Published: (2021)

Damoctocog Alfa Pegol, a PEGylated B-domain Deleted Recombinant Extended Half-life Factor VIII for the Treatment of Hemophilia A: A Product Review
by: Mark T. Reding, et al.
Published: (2024)