Therapeutic Potential of Targeting the PERK Signaling Pathway in Ischemic Stroke

Many pathologic states can lead to the accumulation of unfolded/misfolded proteins in cells. This causes endoplasmic reticulum (ER) stress and triggers the unfolded protein response (UPR), which encompasses three main adaptive branches. One of these UPR branches is mediated by protein kinase RNA-lik...

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Main Authors: Xinyuan Yu (Author), Lihong Dang (Author), Ran Zhang (Author), Wei Yang (Author)
Format: Book
Published: MDPI AG, 2024-03-01T00:00:00Z.
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