Phentolamine mesylate: It's role as a reversal agent for unwarranted prolonged local analgesia

Administration of local anesthesia is an integral procedure prior to dental treatments to minimize the associated pain. It is learned that its effect stays more than the time required for the dental procedure to be completed. This prolonged soft tissue anesthesia (STA) can be detrimental, inconvenie...

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Main Authors: Harpreet Singh Grover (Author), Anil Gupta (Author), Neha Saksena (Author), Neha Saini (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
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100 1 0 |a Harpreet Singh Grover  |e author 
700 1 0 |a Anil Gupta  |e author 
700 1 0 |a Neha Saksena  |e author 
700 1 0 |a Neha Saini  |e author 
245 0 0 |a Phentolamine mesylate: It's role as a reversal agent for unwarranted prolonged local analgesia 
260 |b Wolters Kluwer Medknow Publications,   |c 2015-01-01T00:00:00Z. 
500 |a 0970-4388 
500 |a 1998-3905 
500 |a 10.4103/0970-4388.165646 
520 |a Administration of local anesthesia is an integral procedure prior to dental treatments to minimize the associated pain. It is learned that its effect stays more than the time required for the dental procedure to be completed. This prolonged soft tissue anesthesia (STA) can be detrimental, inconvenient, and unnecessary. Phentolamine mesylate, a Food and Drug Administration-approved drug essentially serves the purpose of faster recovery from numbness at the site of local anesthesia. This article reviews the development of the drug phentolamine mesylate and its indication as a local anesthetic reversal agent. A literature search for phentolamine mesylate as a STA reversal agent was conducted in PubMed using the terms "dental local anesthesia reversal, phentolamine mesylate" up to March 2014. The search was limited to articles published in English. The search revealed 13 PubMed indexed articles stating the development and application of phentolamine mesylate. Phentolamine mesylate is an important step in the progress of developing patient care as well as an aid to the dental clinician. 
546 |a EN 
690 |a Dental local anesthesia 
690 |a local anesthesia reversal 
690 |a phentolamine mesylate 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Journal of Indian Society of Pedodontics and Preventive Dentistry, Vol 33, Iss 4, Pp 265-268 (2015) 
787 0 |n http://www.jisppd.com/article.asp?issn=0970-4388;year=2015;volume=33;issue=4;spage=265;epage=268;aulast=Grover 
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