Glutathione Transferase (GST)-Activated Prodrugs
Glutathione transferase (formerly GST) catalyzes the inactivation of various electrophile-producing anticancer agents via conjugation to the tripeptide glutathione. Moreover, several data link the overexpression of some GSTs, in particular GSTP1-1, to both natural and acquired resistance to various...
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Main Authors: | Andrea Calderan (Author), Paolo Ruzza (Author) |
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Format: | Book |
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MDPI AG,
2013-04-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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