Coumarin Derivatives Act as Novel Inhibitors of Human Dipeptidyl Peptidase III: Combined In Vitro and In Silico Study

• Main Authors: Dejan Agić (Author), Maja Karnaš (Author), Domagoj Šubarić (Author), Melita Lončarić (Author), Sanja Tomić (Author), Zrinka Karačić (Author), Drago Bešlo (Author), Vesna Rastija (Author), Maja Molnar (Author), Boris M. Popović (Author), Miroslav Lisjak (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dipeptidyl peptidase III (DPP III), a zinc-dependent exopeptidase, is a member of the metalloproteinase family M49 with distribution detected in almost all forms of life. Although the physiological role of human DPP III (hDPP III) is not yet fully elucidated, its involvement in pathophysiological pr...