Multi-Compartment 3D-Cultured Organ-on-a-Chip: Towards a Biomimetic Lymph Node for Drug Development

• Main Authors: Aya Shanti (Author), Bisan Samara (Author), Amal Abdullah (Author), Nicholas Hallfors (Author), Dino Accoto (Author), Jiranuwat Sapudom (Author), Aseel Alatoom (Author), Jeremy Teo (Author), Serena Danti (Author), Cesare Stefanini (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The interaction of immune cells with drugs and/or with other cell types should be mechanistically investigated in order to reduce attrition of new drug development. However, they are currently only limited technologies that address this need. In our work, we developed initial but significant buildin...