Association of acute tubular necrosis with gross hematuria in cirrhosis-related immunoglobulin A nephropathy

Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associ...

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Main Authors: Jang Soo Han (Author), So Dug Lim (Author), Won Hyeok Choi (Author), Sung Chul Hong (Author), Jung Hee Park (Author), Eugene Park (Author), Mi Jin Hong (Author), Cho I Lee (Author), Jung Hwan Park (Author), Jong Ho Lee (Author), Jong Oh Song (Author), Young Il Jo (Author)
Format: Book
Published: The Korean Society of Nephrology, 2013-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Jang Soo Han  |e author 
700 1 0 |a So Dug Lim  |e author 
700 1 0 |a Won Hyeok Choi  |e author 
700 1 0 |a Sung Chul Hong  |e author 
700 1 0 |a Jung Hee Park  |e author 
700 1 0 |a Eugene Park  |e author 
700 1 0 |a Mi Jin Hong  |e author 
700 1 0 |a Cho I Lee  |e author 
700 1 0 |a Jung Hwan Park  |e author 
700 1 0 |a Jong Ho Lee  |e author 
700 1 0 |a Jong Oh Song  |e author 
700 1 0 |a Young Il Jo  |e author 
245 0 0 |a Association of acute tubular necrosis with gross hematuria in cirrhosis-related immunoglobulin A nephropathy 
260 |b The Korean Society of Nephrology,   |c 2013-03-01T00:00:00Z. 
500 |a 2211-9132 
500 |a 10.1016/j.krcp.2012.12.003 
520 |a Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associated with gross hematuria is very rare in cirrhosis-related IgAN, although acute renal failure is a frequently reported complication in advanced cirrhosis. Herein, we report an unusual case of ATN requiring renal replacement therapy, associated with gross hematuria in a patient with nonalcoholic, hepatitis B virus-associated cirrhosis. Results of a histopathological analysis revealed obstruction of the lumen of renal tubules by red blood cell casts, a marked tubular necrosis, and IgA deposition in the mesangium. The patient's renal function and gross hematuria were clearly improved after lamivudine treatment. 
546 |a EN 
546 |a KO 
690 |a Cirrhosis 
690 |a Hematuria 
690 |a Lamivudine 
690 |a Renal failure 
690 |a Internal medicine 
690 |a RC31-1245 
690 |a Specialties of internal medicine 
690 |a RC581-951 
655 7 |a article  |2 local 
786 0 |n Kidney Research and Clinical Practice, Vol 32, Iss 1, Pp 43-46 (2013) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2211913212007711 
787 0 |n https://doaj.org/toc/2211-9132 
856 4 1 |u https://doaj.org/article/ae449966f4e34a8d99e53465b53d6471  |z Connect to this object online.