Association of acute tubular necrosis with gross hematuria in cirrhosis-related immunoglobulin A nephropathy
Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associ...
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The Korean Society of Nephrology,
2013-03-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_ae449966f4e34a8d99e53465b53d6471 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Jang Soo Han |e author |
700 | 1 | 0 | |a So Dug Lim |e author |
700 | 1 | 0 | |a Won Hyeok Choi |e author |
700 | 1 | 0 | |a Sung Chul Hong |e author |
700 | 1 | 0 | |a Jung Hee Park |e author |
700 | 1 | 0 | |a Eugene Park |e author |
700 | 1 | 0 | |a Mi Jin Hong |e author |
700 | 1 | 0 | |a Cho I Lee |e author |
700 | 1 | 0 | |a Jung Hwan Park |e author |
700 | 1 | 0 | |a Jong Ho Lee |e author |
700 | 1 | 0 | |a Jong Oh Song |e author |
700 | 1 | 0 | |a Young Il Jo |e author |
245 | 0 | 0 | |a Association of acute tubular necrosis with gross hematuria in cirrhosis-related immunoglobulin A nephropathy |
260 | |b The Korean Society of Nephrology, |c 2013-03-01T00:00:00Z. | ||
500 | |a 2211-9132 | ||
500 | |a 10.1016/j.krcp.2012.12.003 | ||
520 | |a Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria, unlike in cases of idiopathic IgAN. Especially, acute tubular necrosis (ATN) associated with gross hematuria is very rare in cirrhosis-related IgAN, although acute renal failure is a frequently reported complication in advanced cirrhosis. Herein, we report an unusual case of ATN requiring renal replacement therapy, associated with gross hematuria in a patient with nonalcoholic, hepatitis B virus-associated cirrhosis. Results of a histopathological analysis revealed obstruction of the lumen of renal tubules by red blood cell casts, a marked tubular necrosis, and IgA deposition in the mesangium. The patient's renal function and gross hematuria were clearly improved after lamivudine treatment. | ||
546 | |a EN | ||
546 | |a KO | ||
690 | |a Cirrhosis | ||
690 | |a Hematuria | ||
690 | |a Lamivudine | ||
690 | |a Renal failure | ||
690 | |a Internal medicine | ||
690 | |a RC31-1245 | ||
690 | |a Specialties of internal medicine | ||
690 | |a RC581-951 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Kidney Research and Clinical Practice, Vol 32, Iss 1, Pp 43-46 (2013) | |
787 | 0 | |n http://www.sciencedirect.com/science/article/pii/S2211913212007711 | |
787 | 0 | |n https://doaj.org/toc/2211-9132 | |
856 | 4 | 1 | |u https://doaj.org/article/ae449966f4e34a8d99e53465b53d6471 |z Connect to this object online. |