Effect of teduglutide, a glucagon-like peptide-2 analog, in eosinophilic enterocolitis: a case report

We successfully treated a 4-year-old girl with short bowel syndrome and eosinophilic enterocolitis with teduglutide, a glucagon-like peptide-2 analog. Her eosinophilic enterocolitis was cured without relapse, and we were able to increase enteral nutrition. We found that teduglutide had an anti-infla...

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Main Authors: Shoko Ogawa (Author), Ken-ichiro Konishi (Author), Kiyoshi Tanaka (Author), Hajime Takayasu (Author), Yoshimasa Uematsu (Author), Takashi Ito (Author), Hiroyuki Takahashi (Author), Yusuke Kumamoto (Author)
Format: Book
Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
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Summary:We successfully treated a 4-year-old girl with short bowel syndrome and eosinophilic enterocolitis with teduglutide, a glucagon-like peptide-2 analog. Her eosinophilic enterocolitis was cured without relapse, and we were able to increase enteral nutrition. We found that teduglutide had an anti-inflammatory effect in this patient with eosinophilic gastrointestinal disease associated with short bowel syndrome. This report is the first to describe use of teduglutide in the treatment of eosinophilic gastrointestinal disease.
Item Description:2296-2360
10.3389/fped.2024.1457824