Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein

• Main Authors: Paula Andréa Malveira Cavalcante (Author), Natalia Alenina (Author), Alexandre Budu (Author), Leandro Ceotto Freitas-Lima (Author), Thaís Alves-Silva (Author), Juan Sebastian Henao Agudelo (Author), Fatimunnisa Qadri (Author), Niels Olsen Saraiva Camara (Author), Michael Bader (Author), Ronaldo Carvalho Araújo (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages contribute to a continuous increase in blood pressure and kidney damage in hypertension, but their polarization status and the underlying mechanisms have not been clarified. This study revealed an important role for M2 macrophages and the YM1/Chi3l3 protein in hypertensive nephropathy in...