Chemoreactome screening of aquacobalamin and heptamethyl ester of cyanoaquacobyrinic acid cytotoxic effects on tumor cells with experimental confirmation on BT-474 and A549 cell

• Main Authors: I. Yu. Torshin (Author), M. V. Filimonova (Author), O. A. Gromova (Author), L. A. Maiorova (Author), M. A. Sorokina (Author), D. E. Frolova (Author), A. N. Gromov (Author), I. A. Reyer (Author)
• Format: Book
• Published: IRBIS LLC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The search for an effective and safe pharmacotherapy for tumor diseases includes the evaluation of the action of candidate molecules on various types of tumor cells. Vitamin B12 and its derivatives are promising molecules whose properties can be controlled through chemical modifications....