Extrachromosomal circular DNAs in prostate adenocarcinoma: global characterizations and a novel prediction model

• Main Authors: Qingliu He (Author), Qingfu Su (Author), Chengcheng Wei (Author), Pu Zhang (Author), Weihui Liu (Author), Junyi Chen (Author), Xiaoping Su (Author), Wei Zhuang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundThe role of focal amplifications and extrachromosomal circular DNA (eccDNA) is still uncertain in prostate adenocarcinoma (PRAD). Here, we first mapped the global characterizations of eccDNA and then investigate the characterization of eccDNA-amplified key differentially expressed encoded...