Effectiveness of a Spectacle Lens with a Specific Asymmetric Myopic Peripheral Defocus: 12-Month Results in a Spanish Population

• Main Authors: Miguel Ángel Sánchez-Tena (Author), Jose Miguel Cleva (Author), Cesar Villa-Collar (Author), Marta Álvarez (Author), Alicia Ruiz-Pomeda (Author), Clara Martinez-Perez (Author), Cristina Andreu-Vazquez (Author), Eva Chamorro (Author), Cristina Alvarez-Peregrina (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Background: Different designs of ophthalmic lenses have been studied to control the progression of myopia in children. This study aims to evaluate the short-term efficacy of a new design of ophthalmic lens with asymmetric myopic peripheral defocus (MPDL) on myopia progression in children compared to a control group wearing a single-vision lens (SVL). Methods: Children aged 5 to 12 with myopia up to −0.50 D, astigmatism and anisometropia under 1.50 D, and corrected visual acuity over 20/20 were randomized to either the study group (MPDL) or control group (SVL). The myopia progression was evaluated by measuring axial length (AL) growth (IOL Master; Zeiss) over a period of one year. Results: Ninety-two subjects were recruited. Forty-six children were randomly assigned to the control group, and 46 to the study group. In total, 83 children completed the clinical trial, with a mean age of 10.81 [9.53-11.92] years, among which 59.04% were female. After one year of treatment, there was less AL elongation in the study group compared to the control group (0.16 ± 0.16 mm vs. 0.24 ± 0.16 mm, <i>p</i> = 0.034). Conclusions: The MPDL significantly reduced the absolute growth of AL by 39% (<i>p</i> = 0.014) and relative growth of AL by 37.3% (<i>p</i> = 0.012) after 12 months in comparison to the control group in a Spanish population.

Item Description

10.3390/children11020177
2227-9067