Synthesis and biological evaluation of novel tricyclic matrinic derivatives as potential anti-filovirus agents
Twenty-six novel tricyclic sophoridinic and matrinic derivatives containing a common chlorinated benzene fragment were designed, synthesized and evaluated for their anti-ebolavirus (EBOV) activities. Structureactivity relationship analysis indicated: (i) 12N-dichlorobenzyl motif was beneficial for...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2018-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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