Efficacy of core needle biopsy in the diagnosis of pediatric extracranial solid malignancies: A 10-year study

• Main Authors: Arun Kumar Loganathan (Author), Tarun John Jacob (Author), Leni Grace Matthew (Author), Vinu Moses (Author), Shyam Kumar Nidugala Keshava (Author), Anne Jennifer Priscilla (Author), Jujju Jacob Kurian (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 0971-9261; 1998-3891; 10.4103/jiaps.JIAPS_319_20
• Keywords: core needle biopsy; image-guided biopsy; solid malignancies; Pediatrics; RJ1-570; Surgery; RD1-811
• Source: Journal of Indian Association of Pediatric Surgeons, Vol 27, Iss 1, Pp 60-64 (2022)

Introduction: Core needle biopsies of solid masses in children are a minimally invasive technique. It guides to a definitive diagnosis and facilitates management. Aims and Objectives: To determine the accuracy, sensitivity, and specificity of core needle biopsies in diagnosing pediatric solid masses. Materials and Methods: A retrospective analysis of 430 children, who underwent core needle biopsy for solid masses between January 2007 and December 2016 at CMC Vellore, was done. Results: Retroperitoneal and intra-abdominal masses constituted 66% of cases. Real-time image guidance was used in 44% of cases. An accurate diagnosis was obtained in 93.6% of cases, while results did not correlate with the final diagnosis in 3.4%. Three percent had inadequate or necrotic tissue. None of the children had postprocedure complications. Conclusion: Core needle biopsies serve as good diagnostic modality, with minimal risks, in making a conclusive diagnosis and deciding on the line of management.