Therapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorder
Phosphorylation events that occur in response to the second messenger cAMP are controlled spatially and temporally by protein kinase A (PKA) interacting with A-kinase anchoring proteins (AKAPs). Recent advances in understanding the structural basis for this interaction have reinforced the hypothesis...
Saved in:
Main Authors: | Patrick J Nygren (Author), John D. Scott (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2015-07-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Evolutionary Conserved Short Linear Motifs Provide Insights into the Cellular Response to Stress
by: Sergey P. Zavadskiy, et al.
Published: (2022) -
Microbial Biosurfactants: Antimicrobial Activity and Potential Biomedical and Therapeutic Exploits
by: Patricia Puyol McKenna, et al.
Published: (2024) -
From Tyrosine Kinases to Tyrosine Phosphatases: New Therapeutic Targets in Cancers and Beyond
by: Yu Zhou, et al.
Published: (2024) -
Can We Exploit β-Lactamases Intrinsic Dynamics for Designing More Effective Inhibitors?
by: Eleonora Gianquinto, et al.
Published: (2020) -
Tyrosine Kinases and Phosphatases: Enablers of the Porphyromonas gingivalis Lifestyle
by: Richard J. Lamont, et al.
Published: (2022)