Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice

• Main Authors: Ya-Li Yang (Author), Li-Feng Sun (Author), Yan Yu (Author), Tian-Xia Xiao (Author), Bao-Bei Wang (Author), Pei-Gen Ren (Author), Hui-Ru Tang (Author), Jian V. Zhang (Author)
• Format: Book
• Published: BMC, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was to investigate the role of GPR1 in dehydroepiandrosterone (DHEA)-induce...