Mesenchymal Stem Cell-Educated Macrophages Ameliorate LPS-Induced Systemic Response

• Main Authors: Yaoqin Hu (Author), Chaojin Qin (Author), Guoping Zheng (Author), Dengming Lai (Author), Huikang Tao (Author), Yan Zhang (Author), Guanguan Qiu (Author), Menghua Ge (Author), Lanfang Huang (Author), Lina Chen (Author), Baoli Cheng (Author), Qiang Shu (Author), Jianguo Xu (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Both bone marrow and adipose-derived mesenchymal stem cells (ASCs) have immunomodulatory effects. The goal of this study was to determine whether ASCs-educated macrophages could directly ameliorate LPS-induced systemic response in a mouse model. Mouse peritoneal macrophages were cocultured with ASCs...