Genotyping of a tri-allelic polymorphism by a novel melting curve assay in <it>MTHFD1L</it>: an association study of nonsyndromic Cleft in Ireland

• Main Authors: Minguzzi Stefano (Author), Molloy Anne M (Author), Peadar Kirke (Author), Mills James (Author), Scott John M (Author), Troendle James (Author), Pangilinan Faith (Author), Brody Lawrence (Author), Parle-McDermott Anne (Author)
• Format: Book
• Published: BMC, 2012-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Polymorphisms within the <it>MTHFD1L</it> gene were previously associated with risk of neural tube defects in Ireland. We sought to test the most significant <it>MTHFD1L</it> polymorphisms for an association w...