Safety study of extract of medicago sativa sowing grass
<p>In this study there was determined the absence of toxic effect after a single intragastric administration of EGMS at a dose of 5000 mg / kg to male and female rats. According to the conventional toxicological classification of substances, under the intragastric administration EGMS belongs t...
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| Main Authors: | , |
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| Format: | Book |
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Nicolaus Copernicus University in Toruń, Poland - University Sports Center,
2015-02-01T00:00:00Z.
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| Summary: | <p>In this study there was determined the absence of toxic effect after a single intragastric administration of EGMS at a dose of 5000 mg / kg to male and female rats. According to the conventional toxicological classification of substances, under the intragastric administration EGMS belongs to class V of toxicity - practically harmless substances (LD<sub>50</sub><sub> </sub>>5000 mg / kg). The results of macro- and microscopic studies of internal organs in 14 days after a single intragastric administration of EGMS at a dose of 5000 mg / kg showed the absence of any anatomical and morphological disorders in tissue structures of male and female rats. The calculated value of TI, which lies beyond 200, indicates a high level of safety of EGMS and its prospectivity for medical practice as an effective and safe corrector of protein metabolism with an anabolic action.</p> |
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| Item Description: | 2450-6605 2450-6605 10.12775/PPS.2015.01.02.002 |