Implementation of an integrated care strategy for child contacts of tuberculosis patients: a quasi-experimental study protocol

Abstract Background Childhood tuberculosis continues to be a major public health problem. Although the visibility of the epidemic in this population group has increased, further research is needed. Objective To design, implement and evaluate an integrated care strategy for children under five years...

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Main Authors: Dione Benjumea-Bedoya (Author), Esteban Villegas Arbeláez (Author), Daniela Martínez-Peñaloza (Author), Claudia Patricia Beltrán-Arroyave (Author), Andrea Victoria Restrepo Gouzy (Author), Diana Marín (Author), Lina Marcela Cadavid Álvarez (Author), Beatriz Molinares (Author), Fernando Nicolás Montes Zuluaga (Author), Henry Pulido Duarte (Author), Pedro Mauricio Suárez Parra (Author), Juan Carlos Alzate Ángel (Author), Guillermo Vélez-Parra (Author), Teresa Realpe (Author), Marisol Vásquez Villa (Author), Stefani Yamile Ríos Buitrago (Author), Jenifer Puerta Zapata (Author), Lisandra María Arango García (Author), Yesenia Perea Torres (Author), Natalia Pérez Doncel (Author), María Patricia Arbeláez Montoya (Author), Jaime Robledo (Author)
Format: Book
Published: BMC, 2023-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Dione Benjumea-Bedoya  |e author 
700 1 0 |a Esteban Villegas Arbeláez  |e author 
700 1 0 |a Daniela Martínez-Peñaloza  |e author 
700 1 0 |a Claudia Patricia Beltrán-Arroyave  |e author 
700 1 0 |a Andrea Victoria Restrepo Gouzy  |e author 
700 1 0 |a Diana Marín  |e author 
700 1 0 |a Lina Marcela Cadavid Álvarez  |e author 
700 1 0 |a Beatriz Molinares  |e author 
700 1 0 |a Fernando Nicolás Montes Zuluaga  |e author 
700 1 0 |a Henry Pulido Duarte  |e author 
700 1 0 |a Pedro Mauricio Suárez Parra  |e author 
700 1 0 |a Juan Carlos Alzate Ángel  |e author 
700 1 0 |a Guillermo Vélez-Parra  |e author 
700 1 0 |a Teresa Realpe  |e author 
700 1 0 |a Marisol Vásquez Villa  |e author 
700 1 0 |a Stefani Yamile Ríos Buitrago  |e author 
700 1 0 |a Jenifer Puerta Zapata  |e author 
700 1 0 |a Lisandra María Arango García  |e author 
700 1 0 |a Yesenia Perea Torres  |e author 
700 1 0 |a Natalia Pérez Doncel  |e author 
700 1 0 |a María Patricia Arbeláez Montoya  |e author 
700 1 0 |a Jaime Robledo  |e author 
245 0 0 |a Implementation of an integrated care strategy for child contacts of tuberculosis patients: a quasi-experimental study protocol 
260 |b BMC,   |c 2023-01-01T00:00:00Z. 
500 |a 10.1186/s12887-022-03798-x 
500 |a 1471-2431 
520 |a Abstract Background Childhood tuberculosis continues to be a major public health problem. Although the visibility of the epidemic in this population group has increased, further research is needed. Objective To design, implement and evaluate an integrated care strategy for children under five years old who are household contacts of bacteriologically confirmed pulmonary tuberculosis patients in Medellín and the Metropolitan Area. Methods A quasi-experimental study in which approximately 300 children who are household contacts of bacteriologically confirmed pulmonary tuberculosis patients from Medellín and the Metropolitan Area will be evaluated and recruited over one year. A subgroup of these children, estimated at 85, who require treatment for latent tuberculosis, will receive an integrated care strategy that includes: some modifications of the current standardized scheme in Colombia, with rifampicin treatment daily for four months, follow-up under the project scheme with nursing personnel, general practitioners, specialists, professionals from other disciplines such as social work, psychology, and nutritionist. Additionally, transportation and food assistance will be provided to encourage treatment compliance. This strategy will be compared with isoniazid treatment received by a cohort of children between 2015 and 2018 following the standardized scheme in the country. The study was approved by the CIB Research Ethics Committee and UPB. ClinicalTrials.gov identifier NCT04331262. Discussion This study is expected to contribute to the development of integrated care strategies for the treatment of latent tuberculosis in children. The results will have a direct impact on the management of childhood tuberculosis contributing to achieving the goals proposed by the World Health Organization's End TB Strategy. Trial registration ClinicalTrials.gov identifier NCT04331262 . Implementation of an Integrated Care Strategy for Children Contacts of Patients with Tuberculosis. Registered 2 April 2020.  
546 |a EN 
690 |a Latent Tuberculosis 
690 |a Comprehensive Health Care 
690 |a Person-Centered Care 
690 |a Child, Preschool 
690 |a Rifampin 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n BMC Pediatrics, Vol 23, Iss 1, Pp 1-9 (2023) 
787 0 |n https://doi.org/10.1186/s12887-022-03798-x 
787 0 |n https://doaj.org/toc/1471-2431 
856 4 1 |u https://doaj.org/article/afdfd325fe9d48e4bd919e6a68dcb27d  |z Connect to this object online.