The ovarian germinal reserve and apoptosis-related proteins in the infant and adolescent human ovary

• Main Authors: María Itatí Albamonte (Author), Mirta Susana Albamonte (Author), Ricardo M. Bou-Khair (Author), Luis Zuccardi (Author), Alfredo Daniel Vitullo (Author)
• Format: Book
• Published: BMC, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Normal pubertal ovary displays all stages of follicular development and a biased BAX/BCL2 protein ratio in favor of pro-apoptotic BAX protein comparable to the adult ovary. However, adolescents suffering malignant extra-gonadal disease show a limited follicle development after cy...