Association between vitamin D and urinary tract infection in children

• Main Authors: Abolfazl Mahyar (Author), Parviz Ayazi (Author), Sara Safari (Author), Reza Dalirani (Author), Amir Javadi (Author), Shiva Esmaeily (Author)
• Format: Book
• Published: Korean Pediatric Society, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1738-1061; 2092-7258; 10.3345/kjp.2018.61.3.90
• Keywords: 25-Hydroxyvitamin D; Urinary tract infection; Child; Pediatrics; RJ1-570
• Source: Korean Journal of Pediatrics, Vol 61, Iss 3, Pp 90-94 (2018)

PurposeThe present study aimed to determine the relationship between serum 25-hydroxyvitamin D (25(OH)D) level and Urinary tract infections (UTIs) in children.MethodsIn this case-control study, 70 children with UTI (case group) were compared with 70 healthy children (control group) in terms of serum 25(OH)D levels. The children were between 1 month and 12 years of age. Serum 25(OH)D levels were measured using enzyme-linked immunosorbent assay (ELISA). The results were analyzed and compared between both groups.ResultsAmong 70 children with UTI (case group), 5 children (7.2%) were male and 65 (92.8%) were female. Among the healthy children (control group), 9 (12.8%) and 61 children (87.2%) were male and female, respectively (P=0.39). The mean±standard deviation of age in the case and control groups were 53.2±35.6 and 36.1±60.2 months, respectively (P=0.24). The mean level of serum 25(OH)D in the case group was significantly higher than that of the control group (20.4±8.6 ng/mL vs. 16.9±7.4 ng/mL, P=0.01).ConclusionThis study showed that there was a relationship between serum 25(OH)D levels and UTI in children. It seems that 25(OH)D plays a role in the pathogenesis of UTI.