Efficient Gene Silencing by Self-Assembled Complexes of siRNA and Symmetrical Fatty Acid Amides of Spermine

• প্রধান লেখক: Charareh Pourzand (লেখক), Ian S. Blagbrough (লেখক), Abdelkader A. Metwally (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2011-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Gene silencing by siRNA (synthetic dsRNA of 21-25 nucleotides) is a well established biological tool in gene expression studies and has a promising therapeutic potential for difficult-to-treat diseases. Five fatty acids of various chain length and oxidation state (C12:0, C18:0, C18:1, C18:2, C22:1)...