DISTRIBUTION OF R-FACTORS IN GRAM NEGATIVE BACTERIA

• Main Authors: Sh.Hakimi (Author), M.Sigaroodi (Author), M.Mohammadi (Author), B.Ghorayshi (Author), S.Mahajer (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 1981-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2251-6085; 2251-6093
• Keywords: Entero bacteria; Gram negative bacteria; Public aspects of medicine; RA1-1270
• Source: Iranian Journal of Public Health, Vol 10, Iss 1-4 (1981)

A total number of 259 gram negative bacteria (entero-bacteria) isolated during the years 1973-1974 was examined. These strains were isolated from sick children referred and or hospitalized in a children hospital in Tehran. The strains consisted of ; 131E.coli, 52 Salmonella, 40 Klebsiella, 18 Shigella, 13 Proteus, 3 Enterobacter and 2 Citrobacter. Sensitivity tests were performed according to the method of Kerby and Bauer. It was shown that 59% of these bacteria were drug resistant with the majority of the strains carrying resistances to two or more drugs (multiple resistances). Drug resistance was found in 78.9% of Salmonelleae, 77.7% of Shigelleae, 55.5% of Escherichieae, 52.5% of Klebsielleae and 61.5% of Proteae. Further studies have shown that the majority of these resistances were mediated by R-factor. None of the S.typhi strains so far tested was found to be resistant to any of the antimicrobial drugs used in this study.