SRT1720 Alleviates ANIT-Induced Cholestasis in a Mouse Model

• Main Authors: Linxi Yu (Author), Xiaoxin Liu (Author), Zihang Yuan (Author), Xiaojiaoyang Li (Author), Hang Yang (Author), Ziqiao Yuan (Author), Lixin Sun (Author), Luyong Zhang (Author), Zhengzhou Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intrahepatic cholestasis is a kind of clinical syndrome along with hepatotoxicity which caused by intrahepatic and systemic accumulations of bile acid. There are several crucial generating factors of the pathogenesis of cholestasis, such as inflammation, dysregulation of bile acid transporters and o...