N-terminal region is responsible for mHv1 channel activity in MDSCs

• Автори: Antonio Peña-Pichicoi (Автор), Miguel Fernández (Автор), Nieves Navarro-Quezada (Автор), Juan J. Alvear-Arias (Автор), Christian A. Carrillo (Автор), Emerson M. Carmona (Автор), Jose Garate (Автор), Angelica M. Lopez-Rodriguez (Автор), Alan Neely (Автор), Erick O. Hernández-Ochoa (Автор), Carlos González (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Voltage-gated proton channels (Hv1) are important regulators of the immunosuppressive function of myeloid-derived suppressor cells (MDSCs) in mice and have been proposed as a potential therapeutic target to alleviate dysregulated immunosuppression in tumors. However, till date, there is a lack of ev...