Skin Tests of a Novel Nicotine Patch, PHK-301p, in Healthy Male Volunteers: Phase I, Placebo-Controlled Study

• Autores principales: Shin Irie (Autor), Hiroshi Tsukikawa (Autor), Toshitaka Nabeshima (Autor), Makiko Usami (Autor), Tadaaki Karino (Autor), Shuichi Komatsu (Autor), Moriaki Akasaki (Autor)
• Formato: Libro
• Publicado: Elsevier, 2006-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Major local adverse reactions in the nicotine patches are skin reactions. To assess the skin reaction of PHK-301p, a newly developed nicotine patch, we conducted a phase I study that consisted of 2 parts: a skin irritation test (48-h closed patch test) and a photosensitivity test (24-h closed patch...