Successful Treatment in a Child with Refractory Periungual Warts by Local Hyperthermia: A Case Report

• Main Authors: Du L (Author), Cao Z (Author), Liu Z (Author), Zhu X (Author), Zhang C (Author)
• Format: Book
• Published: Dove Medical Press, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Lingyun Du,* Zhiqiang Cao,* Zhaoyang Liu, Xia Zhu, Chunhong Zhang Department of Dermato-Venereology, The Second Hospital of Shandong University, Jinan, People's Republic of China*These authors contributed equally to this workCorrespondence: Chunhong Zhang, Department of Dermato-Venereology, The Second Hospital of Shandong University, Jinan, People's Republic of China, Tel [phone], Fax [phone], Email [e-mail]: Periungual wart is a kind of verruca vulgaris that occurs alongside or underlying the nails, which is challenging to treat and prone to recurrence, seriously affecting the quality of patients' life. We report a 6-year-old boy with periungual warts who had experienced various treatments with no improvement and even worsening. Therefore, we tried to treat the patient with local hyperthermia which uses a patented device that has an infrared emission source. The heat generated by infrared rays acts on the local skin surface. The mechanism of this therapy may be to establish a specific immune response against human papillomavirus-infected tissues, thereby facilitating the clearance of human papillomavirus at irradiated and non-irradiated sites. Local hyperthermia has the advantages of non-contact, safety, noninvasive, less pain, and so on. After 5 treatments, the irradiated periungual warts completely cleared after 2 weeks. The unirradiated sites were almost cured after 7 weeks. This case suggests that local thermotherapy has shown great advantages in the treatment of these refractory periungual warts and offers a new and effective therapy in patients with periungual warts.Keywords: child, local hyperthermia, periungual warts, refractory warts

Item Description

1178-7015