An unusual case of chronic lymphocytic leukemia, multiple myeloma and cardiac amyloidosis

Light chain amyloidosis has very rarely been reported in association with chronic lymphocytic leukemia (CLL). We reported on a 76-years-old female who presented with simultaneous kappa-restricted chronic lymphocytic leukemia (CLL) and a lambda-restricted multiple myeloma with plasma cells causing AL...

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Bibliographic Details
Main Authors: Dongyan Liu (Author), Hakim T. Uqdah (Author), Alisha D. Gordy (Author)
Format: Book
Published: Greater Baltimore Medical Center, 2017-10-01T00:00:00Z.
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Summary:Light chain amyloidosis has very rarely been reported in association with chronic lymphocytic leukemia (CLL). We reported on a 76-years-old female who presented with simultaneous kappa-restricted chronic lymphocytic leukemia (CLL) and a lambda-restricted multiple myeloma with plasma cells causing AL amyloidosis involving the heart. While monoclonal immunoglobulins occasionallyproduced by CLL have previously been implicated in AL amyloidosis, there only a few cases reported of AL amyloidosis resulting from a distinct plasma cell dyscrasia that is not clonally related to the concurrent CLL.
Item Description:2000-9666
10.1080/20009666.2017.1370940