Microbiologic evaluation of efficacy of probiotic for correction intestinal disbiosis

• Main Authors: Nelya Bissenova (Author), Aigerim Yergaliyeva (Author), Kaiyrgeldy Makhambetov (Author), Nurkiya Talgatbekova (Author)
• Format: Book
• Published: National Scientific Medical Center, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<b>Purpose of the study.</b> To determine the microbiological efficacy of probiotics in the intestinal dysbiosis correction in patients with gastroenterological diseases.<br> <b>Methods.</b> A prospective bacteriologic research of intestinal dysbiosis of 47 adult patients (36 women (76.5%), 11 men (23.4%), the average age of 38.0 ± 2.1). The first group consisted of patients with gastroenterological diseases (n = 47). Second group - these same patients after correction with probiotics (n = 23). We conducted qualitative and quantitative analysis of intestinal microbiota both groups.<br> <b>Results.</b> Intestinal microbiocenosis of patients in both groups was included as the obligatory and facultative microflora. In the first group the contents of bifidobacteria in the amount of 108 CFU/g or more was 65.9%, lactobacilli in an amount of 106 CFU/g or higher at 17.0%, E.coli with normal enzymatic activity in an amount of 107 CFU/g or higher in 55.3% of patients, in the second group these indicators were 78.3%, 56.5% and 73.9%, respectively. From facultative microflora in the first group noted the high content of Candida - 4.2%, lactose-negative E.coli - 6.3% and fungi in 8.5% of patients, in the second group these indicators not detected.<br> <b>Conclusion.</b> Thus, the intestinal microflora of patients after correction of probiotics, is characterized by a significant increase in the number of obligate microflora: lactobacilli, bifidobacteria, E. coli with normal enzymatic activity and reduced the number of Candida, lactose-negative E.coli and fungi.

Item Description

1812-2892
2313-1519
10.23950/1812-2892-2016-2-36-42